Name | Bremelanotide (PT141) |
Molecular Formula | C50H68N14O10 |
CAS | 32780-32-8 |
Sequence | |
Molecular Weight | 1025.2 |
Purity (HPLC) | 98%min |
Appearance | White powder |
Single Impurity(HPLC) | 1%max |
Amino Acid Composition | ±10% of theoretical |
Peptide Content(N%) | ≥80.0% |
Water Content(KF) | ≤6.0% |
Acetate Content(HPLC) | ≤15% |
MS(ESI) | Consistent |
Mass Balance | 95.0~105.0% |
PT141 (Bremelanotide) is a cyclic hepta-peptide lactam analog of alpha-melanocyte-stimulating hormone (alpha-MSH) that activates the melanocortin receptors MC3-R and MC4-R in the central nervous system. It is the generic term for a new medication for use in treating sexual dysfunction in men (erectile dysfunction or impotence) as well as sexual dysfunction in women (sexual arousal disorder). It is a synthetic aphrodisiac. Unlike Viagra and other related medications, it does not act upon the vascular system, but directly increases sexual desire.