Bremelanotide (PT141)

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NameBremelanotide (PT141)
Molecular FormulaC50H68N14O10
CAS32780-32-8
Sequence
Molecular Weight1025.2
Purity (HPLC)98%min
AppearanceWhite powder
Single Impurity(HPLC)1%max
Amino Acid Composition±10% of theoretical
Peptide Content(N%)≥80.0%
Water Content(KF)≤6.0%
Acetate Content(HPLC)≤15%
MS(ESI)Consistent
Mass Balance95.0~105.0%

PT141 (Bremelanotide) is a cyclic hepta-peptide lactam analog of alpha-melanocyte-stimulating hormone (alpha-MSH) that activates the melanocortin receptors MC3-R and MC4-R in the central nervous system. It is the generic term for a new medication for use in treating sexual dysfunction in men (erectile dysfunction or impotence) as well as sexual dysfunction in women (sexual arousal disorder). It is a synthetic aphrodisiac. Unlike Viagra and other related medications, it does not act upon the vascular system, but directly increases sexual desire.

Jennifer Setchfield

Author